Unexpected off-target edits may occur when CRISPR/Cas systems do not exclusively cut the intended target area, which could lead to potentially harmful consequences, such as the activation of oncogenes.
paraphrase:
Unforeseen off-target edits can be generated when the CRISPR/Cas systems do not cleave only the target region, and may cause potentially harmful effects, for example by activation of oncogenes.[
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