Question

cystic fibrosis is an inherited disorder that is caused when three bases are accidentally removed from the CFTR gene. which of the following is TRUE/

cystic fibrosis is caused by a deletion mutation
it is not known why cystic fibrosis happens in people
the affects of cystic fibrosis only impact women
cystic fibrosis is caused by an inversion mutation

Answer 1

The statement that is TRUE is:

**Cystic fibrosis is caused by a deletion mutation.**

Cystic fibrosis is caused by a mutation in the CFTR gene, and one of the most common mutations is a deletion of three DNA bases (which results in the loss of phenylalanine at position 508 of the protein). The other statements are not correct:

- It is known that cystic fibrosis is an inherited disorder caused by mutations in the CFTR gene.
- The effects of cystic fibrosis impact both males and females, not just women.
- The mutation responsible for cystic fibrosis is not an inversion mutation; it is primarily a deletion or point mutation.