To simplify the expression \( x^3(2 + y^5) \), we can use the distributive property.
Distributing \( x^3 \) to both terms inside the parentheses gives us:
\[ x^3 \cdot 2 + x^3 \cdot y^5 = 2x^3 + x^3y^5 \]
None of the provided options matched this expression exactly. However, the expression \( 2x^3 + x^3y^5 \) is the correct simplification of \( x^3(2 + y^5) \).
So the closest answer to our simplified expression would be \( 2x^3 + x^3y^5 \).
Final Answer: 2x^3 + x^3y^5.