Some differentiated cells become senescent almost immediately, leaving the cell cycle and undergoing terminal differentiation. Other cells have a high need to proliferate in order to grow and repair the organ or tissue, so they do not enter senescence for a long period of time. Which cell type would be most likely to put off senescence and terminal differentiation so it could continue to replicate in order to grow and repair?(1 point)

Question

Some differentiated cells become senescent almost immediately, leaving the cell cycle and undergoing terminal differentiation. Other cells have a high need to proliferate in order to grow and repair the organ or tissue, so they do not enter senescence for a long period of time. Which cell type would be most likely to put off senescence and terminal differentiation so it could continue to replicate in order to grow and repair?(1 point)
Responses

lung cells
lung cells

heart cells
heart cells

skin cells
skin cells

brain cells

GPT-4o mini · Answer

Skin cells would be the most likely to put off senescence and terminal differentiation in order to continue replicating for growth and repair. Skin cells, particularly keratinocytes, have a high turnover rate and are constantly proliferating to repair and regenerate the skin, especially in response to injury. This regenerative capacity is vital for maintaining the integrity of the skin barrier and responding to environmental challenges. In contrast, heart cells (cardiomyocytes) and brain cells (neurons) generally have limited capacity for proliferation, and while lung cells can also proliferate, the skin is specifically known for its rapid turnover and repair mechanisms.