To divide fractions, you multiply the first fraction by the reciprocal of the second fraction.
So, to divide \( -\frac{3}{4} \) by \( \frac{3}{8} \):
\[ -\frac{3}{4} \div \frac{3}{8} = -\frac{3}{4} \times \frac{8}{3} \]
Now, multiply the numerators and the denominators:
\[ = -\frac{3 \times 8}{4 \times 3} = -\frac{24}{12} \]
Now, simplify \( -\frac{24}{12} \):
\[ = -2 \]
Thus, the quotient when you divide \( -\frac{3}{4} \) by \( \frac{3}{8} \) is \( -2 \).
The correct response is:
−2