To simplify \(\frac{2^{17}}{2^{-5}}\), we can use the property of exponents that states:
\[ \frac{a^m}{a^n} = a^{m-n} \]
Applying this to our expression:
\[ \frac{2^{17}}{2^{-5}} = 2^{17 - (-5)} = 2^{17 + 5} = 2^{22} \]
Thus, the simplified form of \(\frac{2^{17}}{2^{-5}}\) is:
\[ \boxed{2^{22}} \]