To simplify the expression \( \frac{12^{53}}{7^{53}} \) using the Quotient Rule of Integer Exponents, we start by applying the rule which states:
\[ \frac{a^m}{b^m} = \left(\frac{a}{b}\right)^m \]
In this case, \( a = 12 \), \( b = 7 \), and \( m = 53 \). Therefore, we can rewrite the expression as follows:
\[ \frac{12^{53}}{7^{53}} = \left(\frac{12}{7}\right)^{53} \]
So, the simplified expression is:
\[ \left(\frac{12}{7}\right)^{53} \]