The best explanation for the effects of the Yamasee War on the restructuring of settlements and shift in power in South Carolina is:
Indigenous power declined, while colonial power increased.
The Yamasee War (1715-1717) resulted in significant losses for Indigenous groups who participated in the conflict, leading to a decline in their power and influence in the region. In contrast, British colonizers solidified their control, leading to an increase in colonial power and the expansion of settlements.