To construct the polynomial function based on the given zeros and their multiplicities:
- The zero \( x = 4 \) has a multiplicity of 1, which means it contributes the factor \( (x - 4) \).
- The zero \( x = -2 \) has a multiplicity of 3, which means it contributes the factor \( (x + 2)^3 \).
Putting these together, the polynomial function can be expressed as:
\[ f(x) = (x - 4)(x + 2)^3. \]
Therefore, the correct response is:
f(x) = (x - 4)(x + 2)³.