To identify a substitution mutation in the given sequences, we need to compare each sequence with the original DNA sequence:
Original Sequence:
C G T T A C T G C A A T G C A A T G A C G T T A
Now, let's break down the provided sequences:
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C G T C T A C T G C A A T G C A G A T G A C G T T A
- A substitution occurs in the first position and the second-to-last position.
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C G T C T A C T G C A A T G C A G A T G A C G T T A
- Same as above, same substitutions.
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C G T A C T G C A A T G C A T G A C G T T A
- Substitutions occur: in the first and middle position (first A changed to T).
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C G T A C T G C A A T G C A T G A C G T T A
- Same as above, same substitutions.
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C G T T A C T G C A A T G C A T G A C G T T A
- No substitutions.
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C G T T A C T G C A A T G C A A T G A C G T T A
- No substitutions.
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C G T G A C T G C A A T G C A C T G A C G T T A
- The second-to-first position has a mutation.
For a substitution mutation, we need to look for sequences that have changed a single nucleotide compared to the original. In this case, any sequence with just one single difference from the original sequence qualifies.
The sequences that exhibit these conditions have distinct substitutions when compared to the original sequence. Therefore:
- The right answers for substitution mutations are:
- First sequence
- Second sequence
- Third sequence (the C-T substitution).
So, confirm the sequences you're particularly interested in or you think exhibit a substitution. If the goal is merely to find mutations, then options 1, 2, and 3 show those.
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