The sentence that best helps develop the idea expressed in paragraph 2 is:
C. Thanks to this analysis, the researchers were able to narrow down their original list of 3,000 genes to 43 specific sequences that might have contributed to Lonesome George’s long, disease-free life.
This sentence elaborates on the researchers' findings about the giant tortoises' genetics and relates directly to the efforts to understand the mechanisms of aging and health, which aligns with the focus of paragraph 2.