During a chemical reaction, the total number of atoms is conserved. This means that the atoms present in the reactants are rearranged to form the products, but no atoms are created or destroyed in the process. This principle is a fundamental aspect of the law of conservation of mass, which states that mass cannot be created or destroyed in a closed system.
For example, if a chemical reaction starts with 10 atoms of various elements in the reactants, the products will also contain a total of 10 atoms, although they may be bonded in different ways or exist in different molecular forms.