The best response that accurately describes how the respiratory system and circulatory system interact is:
In the lungs, oxygen is transferred to the blood and carried by red blood cells. Once it is distributed, the red blood cells pick up carbon dioxide and transport it back to the lungs, where it is transferred to the lungs so it can be exhaled.
This explanation correctly outlines the process of gas exchange in the lungs, where oxygen is absorbed into the bloodstream and carbon dioxide is released to be exhaled.