To simplify the expression \( -4(2x + 5) \), we should use the distributive property. This means we will multiply \(-4\) by each term inside the parentheses.
So we have:
\[ -4(2x + 5) = -4 \cdot 2x + (-4) \cdot 5 \]
Calculating each term gives:
\[ -4 \cdot 2x = -8x \] \[ -4 \cdot 5 = -20 \]
Putting it all together, we get:
\[ -8x - 20 \]
Thus, the simplified expression is \( -8x - 20 \).
None of the provided options correspond to this correct answer, so it seems there might have been an oversight in the responses given.