The true statements about hypothyroidism are:
-
Caused by the autoimmune destruction of thyroid tissue - This is true, as Hashimoto's thyroiditis, an autoimmune condition, is a common cause of hypothyroidism.
-
Testing should be done for individuals with an unexplained weight gain - This is also true. Unexplained weight gain can be a symptom of hypothyroidism, and testing thyroid function is recommended in such cases.
-
Associated with reduced metabolic rate, weight gain, and increased risk of overweight and obesity - This statement is true as well. Hypothyroidism leads to a reduced metabolic rate, which can contribute to weight gain and an increased risk of obesity.
-
There are no effective therapies for the weight gain associated with hypothyroidism - This statement is false. While managing weight can be challenging, there are effective therapies for hypothyroidism, typically involving thyroid hormone replacement therapy that can help normalize metabolic function and assist with weight management.
So, the true statements are 1, 2, and 3.