Question
Hypofunction of an endocrine gland is associated with which of the following? Select all that apply.
Hashimoto’s thyroiditis
Graves’ disease
Central diabetes insipidus
Syndrome of inappropriate antidiuretic hormone
Acromegaly
Hashimoto’s thyroiditis
Graves’ disease
Central diabetes insipidus
Syndrome of inappropriate antidiuretic hormone
Acromegaly
Answers
GPT-4o mini
Hypofunction of an endocrine gland refers to decreased hormone production from that gland. Based on the conditions you provided, the following are associated with hypofunction:
1. **Hashimoto’s thyroiditis** - This is an autoimmune condition that leads to hypothyroidism (hypofunction of the thyroid gland).
2. **Central diabetes insipidus** - This condition involves a deficiency of vasopressin (antidiuretic hormone) due to dysfunction of the posterior pituitary, which can be seen as a hypofunction.
The other conditions listed are associated with hyperfunction or increased hormone production:
- **Graves’ disease** - This is characterized by hyperfunction of the thyroid gland, leading to hyperthyroidism.
- **Syndrome of inappropriate antidiuretic hormone (SIADH)** - In this condition, there is excessive secretion of antidiuretic hormone, leading to water retention and hyponatremia, indicating hyperfunction.
- **Acromegaly** - This is caused by excess growth hormone, typically due to a pituitary adenoma, representing hyperfunction.
Thus, the correct answers for hypofunction of an endocrine gland are:
- Hashimoto’s thyroiditis
- Central diabetes insipidus
1. **Hashimoto’s thyroiditis** - This is an autoimmune condition that leads to hypothyroidism (hypofunction of the thyroid gland).
2. **Central diabetes insipidus** - This condition involves a deficiency of vasopressin (antidiuretic hormone) due to dysfunction of the posterior pituitary, which can be seen as a hypofunction.
The other conditions listed are associated with hyperfunction or increased hormone production:
- **Graves’ disease** - This is characterized by hyperfunction of the thyroid gland, leading to hyperthyroidism.
- **Syndrome of inappropriate antidiuretic hormone (SIADH)** - In this condition, there is excessive secretion of antidiuretic hormone, leading to water retention and hyponatremia, indicating hyperfunction.
- **Acromegaly** - This is caused by excess growth hormone, typically due to a pituitary adenoma, representing hyperfunction.
Thus, the correct answers for hypofunction of an endocrine gland are:
- Hashimoto’s thyroiditis
- Central diabetes insipidus