If you are referring to a TALC (talcum powder) product with a specific percentage of purity or concentration, it’s generally not recommended to use talcum powder on a mattress. Talc can create a mess, may attract dust or other particles, and can cause issues with moisture retention, which might lead to mold or mildew.
If you’re looking to freshen up your mattress or reduce moisture, consider using baking soda instead, as it can help absorb odors and moisture without the concerns associated with talc. Always check the manufacturer's recommendations for your specific mattress before applying any products.