Function of white petrolatum in preparation of white wax ointment?

1 answer

White petrolatum, also known as petroleum jelly, serves several important functions in the preparation of white wax ointment:

  1. Base Formation: White petrolatum acts as a primary ointment base. It provides the desired consistency and texture, allowing for easy application and spreadability on the skin.

  2. Emollient Properties: It has excellent emollient properties that help to soften and soothe the skin. This is particularly beneficial for dry or irritated skin.

  3. Hydration: White petrolatum creates a barrier on the skin's surface, reducing transepidermal water loss and helping to maintain skin hydration.

  4. Stability: It helps to stabilize the formulation, ensuring that the mixture remains homogeneous and does not separate over time.

  5. Occlusive Layer: As an occlusive agent, white petrolatum prevents moisture loss and protects the skin from external irritants and contaminants.

  6. Compatibility: It is generally well-tolerated and compatible with a wide range of active pharmaceutical ingredients, making it suitable for various formulations.

Overall, white petrolatum plays a crucial role in enhancing the effectiveness and usability of white wax ointment for dermatological applications.