To find the circumference of a wheel, use the formula:
\[ C = \pi \times d \]
where \( C \) is the circumference and \( d \) is the diameter. Given the diameter of the wheel is 21 inches and using \( \pi \approx 3.14 \):
\[ C = 3.14 \times 21 \]
Now, calculate the product:
\[ C = 3.14 \times 21 = 65.94 \]
When rounding to the nearest tenth, 65.94 rounds to 65.9.
So, the circumference of the wheel is:
\[ \boxed{65.9 \text{ in}} \]
The correct answer is D) 65.9 in.