The first step in simplifying the expression \((2x^3−12x^2+5x−3)−(7x^3+10x^2−3x+20)\) is to distribute the negative to the second set of parentheses.
This means you'll need to change the signs of each term inside the second set of parentheses before moving on to combine like terms. So the correct choice is:
Distribute the negative to the second set of parentheses.