To expand the expression \((2x + 5)(2x - 5)\), we can use the difference of squares formula, which states that \((a+b)(a-b) = a^2 - b^2\).
Here, we can identify:
- \(a = 2x\)
- \(b = 5\)
Applying the formula:
\[ (2x + 5)(2x - 5) = (2x)^2 - (5)^2 \]
Now calculate each square:
\[ (2x)^2 = 4x^2 \] \[ (5)^2 = 25 \]
Putting it together:
\[ (2x + 5)(2x - 5) = 4x^2 - 25 \]
Thus, the expansion of \((2x + 5)(2x - 5)\) is:
\[ \boxed{4x^2 - 25} \]