First, we need to evaluate the exponents inside the parentheses:
(5 + 1)^2 = 6^2 = 36
(9 - 5)^2 = 4^2 = 16
Now we substitute these values back into the expression:
36 - 16 x 3
Now we need to perform the multiplication before subtraction:
36 - (16 x 3) = 36 - 48
Finally, perform the subtraction:
36 - 48 = -12
Therefore, the final result is -12.