Acetic acid has the formula CH3COOH. At low pH this protonated, uncharged form is the most abundant form in solution. As the pH increases, more of the molecule becomes negatively charged acetate: CH3COO–. At which pH will more of the molecule cross the membrane?

Question

Acetic acid has the formula CH3COOH. At low pH this protonated, uncharged form is the most abundant form in solution. As the pH increases, more of the molecule becomes negatively charged acetate: CH3COO–. At which pH will more of the molecule cross the membrane?
10
8
9
4

GPT 3.5 · Answer

At a pH of 4, more of the molecule will cross the membrane as the majority of the molecule will be in the protonated, uncharged form (CH3COOH) at low pH.