Question

In the case of an autosomal dominant disorder, what is the probability of having an affected child if the mother is unaffected and the father is homozygous dominant?

Answer 1

If the father is homozygous dominant (AA) for an autosomal dominant disorder, all of his offspring will inherit at least one copy of the dominant allele. Therefore, the probability of having an affected child when the mother is unaffected is 100%.