Question

Acute poisoning with acetaminophen often requires the use of a specific
antidote. The beneficial property of this antidote is that it
A. supplies sulfhydryl groups to detoxify a reactive metabolite
B. induces P450 enzymes to enhance elimination
C. blocks the metabolism of acetaminophen
D. enhances renal clearance of acetaminophen
E. chelates acetaminophen

Answers

GPT 3.5
A. supplies sulfhydryl groups to detoxify a reactive metabolite

The specific antidote for acetaminophen poisoning is N-acetylcysteine, which supplies sulfhydryl groups to detoxify the reactive metabolite produced during the metabolism of acetaminophen.