is mercapturic acid is metabolite of acetaminophen

Answer 1

Yes, mercapturic acid is a metabolite of acetaminophen (also known as paracetamol). Acetaminophen is primarily metabolized in the liver through two major pathways, one of which involves the formation of a reactive metabolite called N-acetyl-p-benzoquinone imine (NAPQI). NAPQI can undergo further reactions with cellular molecules, including glutathione, to form mercapturic acid conjugates. These mercapturic acid conjugates are then excreted in the urine.