Question
Chronic myeloid leukemia (CML) is a genetic disorder associated with the Philadelphia chromosome. The Philadelphia chromosome is a mutation in chromosome 22. Part of chromosome 22 is exchanged with part of chromosome 9, bringing together two genes on chromosome 22 and causing a malignancy. What type of mutation occurs in the Philadelphia chromosome?
A.
duplication
B.
insertion
C.
inversion
D.
substitution
E.
translocation
A.
duplication
B.
insertion
C.
inversion
D.
substitution
E.
translocation
Answers
GPT 3.5
E. translocation