-22 2/5 - 1 1/4 x (-2 1/2) =

How do i work that out??

Decide which operation to perform first. Your single pair of parentheses around one number does not help. Is it
(-22 2/5 - 1 1/4) x -2 1/2
or
-22 2/5 - (1 1/4 x -2 1/2) ?
They are not the same.