Question

which organ of our body cannot use GLUT1 and GLUT 3

Answer 1

The liver is one organ of our body that does not use GLUT1 and GLUT3 transporters to uptake glucose. Instead, the liver primarily uses GLUT2 transporters for the uptake of glucose. GLUT2 transporters have a higher Km value and allow for the facilitated diffusion of glucose into the liver cells at a glucose concentration much higher than normal physiological levels. This allows the liver to remove excess glucose from the bloodstream and store it as glycogen or convert it into other metabolites.