what are target organ of parathyroid hormone

Answer 1

The target organs of parathyroid hormone (PTH) are the bones, kidneys, and intestines.

1. Bones: Parathyroid hormone stimulates the activity of osteoclasts, cells responsible for breaking down bone tissue. In turn, this promotes the release of calcium ions from the bone matrix into the bloodstream.

2. Kidneys: PTH acts on the renal tubules in the kidneys, increasing the reabsorption of calcium and decreasing the reabsorption of phosphate. It also stimulates the production of active vitamin D (calcitriol), which aids in the absorption of calcium from the intestines.

3. Intestines: PTH indirectly influences the intestines by stimulating the production of calcitriol, which enhances the absorption of calcium from consumed food.

Overall, PTH plays a vital role in regulating calcium and phosphate levels in the body by acting on these target organs.