what is the relationship between posterior pituitary gland and magnocellular neuroseceretory cells

Answer 1

The posterior pituitary gland and magnocellular neurosecretory cells have a close relationship as the gland is where these cells release their hormones.

The magnocellular neurosecretory cells are located in the hypothalamus of the brain. These cells produce two important hormones called oxytocin and vasopressin (also known as antidiuretic hormone or ADH). These hormones are synthesized in the cell bodies of the magnocellular neurosecretory cells.

However, the magnocellular neurosecretory cells do not directly release these hormones into the bloodstream. Instead, they send their hormone-rich axons down the hypothalamo-neurohypophysial tract to the posterior pituitary gland.

The axons of these cells end in the posterior pituitary gland, which acts as a storage site for the hormones. When appropriate signals are received, the hormones are then released into the bloodstream from the posterior pituitary gland. This allows oxytocin and vasopressin to travel to their target organs and exert their effects on various bodily functions such as uterine contractions, milk ejection, and regulation of water balance.

In summary, the posterior pituitary gland serves as the site of release for hormones produced by magnocellular neurosecretory cells, allowing these hormones to be transported throughout the body to carry out their physiological roles.