in purine degradation what is the difference between xanthine oxidase which used first and second

Answer 1

In purine degradation, xanthine oxidase is responsible for the conversion of hypoxanthine to xanthine, and then xanthine to uric acid.

The first use of xanthine oxidase is in the conversion of hypoxanthine to xanthine. Hypoxanthine is an intermediate molecule in the degradation of purines, which are components of DNA and RNA. Xanthine oxidase catalyzes the oxidation of hypoxanthine, removing two hydrogen atoms and adding molecular oxygen to produce xanthine.

The second use of xanthine oxidase is in the conversion of xanthine to uric acid. After the conversion of hypoxanthine to xanthine, xanthine oxidase continues to act on xanthine. It oxidizes xanthine by removing two hydrogen atoms and adding molecular oxygen to produce uric acid.

Overall, xanthine oxidase plays a crucial role in the metabolism of purines, converting hypoxanthine and xanthine into uric acid, which is eventually excreted from the body.