What was the most significant result of the spanish colonization of central and south America?

Question

Spain became rich by taking the wealth of American colonies.
Thousands of native died from diseases brought from europe
Spain was transformed by the cultural richness of the new world
spain brough religion and moral values to the british colonies

Answer 1

The most significant result of the Spanish colonization of Central and South America was that Spain became rich by taking the wealth of American colonies.