Classification of lipid-derived autacoids

1 answer

1. Prostaglandins: These are lipid-derived autacoids that play a crucial role in inflammation, pain, and fever regulation. They are produced from arachidonic acid and are involved in various physiological processes, including blood vessel constriction/dilation and immune response modulation.

2. Thromboxanes: These autacoids are derived from arachidonic acid and are involved in platelet aggregation and blood clotting.

3. Leukotrienes: These are lipid mediators derived from arachidonic acid and are involved in the regulation of inflammation, immune response, and bronchoconstriction.

4. Lipoxins: These autacoids are derived from arachidonic acid and have anti-inflammatory properties. They play a role in the resolution of inflammation.

5. Eicosanoids: This is a broad class of lipid-derived autacoids that includes prostaglandins, thromboxanes, leukotrienes, and lipoxins. They are involved in various physiological processes, including inflammation, blood clotting, and immune response regulation.

6. Platelet-activating factor (PAF): This lipid-derived autacoid is involved in platelet aggregation, inflammation, and allergic reactions.

7. Sphingolipids: This class of lipid-derived autacoids includes sphingosine-1-phosphate (S1P) and ceramides. S1P is involved in various physiological processes, including blood vessel formation, immune cell trafficking, and regulation of vascular permeability.

8. Endocannabinoids: These lipid-derived autacoids include substances such as anandamide and 2-arachidonoylglycerol (2-AG). They interact with cannabinoid receptors in the body and are involved in various processes, including pain modulation, appetite regulation, and immune response modulation.

9. Resolvins: These autacoids are derived from omega-3 fatty acids and play a role in the resolution of inflammation.

10. Neuroprotectins: These lipid-derived autacoids are derived from omega-3 fatty acids and have neuroprotective properties. They are involved in the regulation of neuronal function and inflammation in the central nervous system.