what is the differende bettween dideoxyribose and deoxyribose
1 answer
Dideoxyribose is a modified form of the sugar deoxyribose that lacks a hydroxyl group on the 3' carbon atom. Deoxyribose is a five-carbon sugar molecule found in nucleotides that make up DNA. The difference between the two is that deoxyribose has a hydroxyl group on both the 2' and 3' carbon atoms, whereas dideoxyribose lacks the hydroxyl group on the 3' carbon atom. This difference affects the ability of nucleotides containing dideoxyribose to form phosphodiester bonds and therefore, DNA sequencing reactions.