Let's simplify the expression \( 2^6 - \frac{2^4}{2^2} \).
First, we can simplify \(\frac{2^4}{2^2}\) using the properties of exponents:
\[ \frac{2^4}{2^2} = 2^{4-2} = 2^2 \]
Now, substitute \(2^2\) back into the original expression:
\[ 2^6 - 2^2 \]
Next, we calculate \(2^6\) and \(2^2\):
\[ 2^6 = 64 \] \[ 2^2 = 4 \]
Now we can perform the subtraction:
\[ 64 - 4 = 60 \]
Thus, the final result is:
\[ \boxed{60} \]