If a graded receptor potential makes the resting membrane potential of the axon more negative (hyperpolarization), you would expect a decrease in the likelihood of generating an action potential.
In general, the generation of action potentials is influenced by the membrane potential reaching a certain threshold (typically around -55 mV in many neurons). Hyperpolarization means that the membrane potential is moving further away from this threshold. As a result:
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Decreased excitability: The neuron becomes less excitable because further depolarization is required to reach the threshold for an action potential.
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Less likelihood of action potential generation: If the graded potential is significant enough to push the resting potential to -75 mV, it means the neuron is less likely to fire an action potential in response to subsequent stimuli unless they are of higher intensity.
In summary, hyperpolarization would typically inhibit neuronal firing, making it more difficult for the neuron to activate and transmit signals.
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