1) How does the pH of a solution affect its solubility and structure of weak organic acids and bases, such as proteins and nucleic acids?

2) Why would a zipper or a Velcro strip be a good analogy to weak interactions between biological molecules?

Thank you!

1 answer

It makes sense to me that it is a weak acid. Here is why-
1. weak acid can react with strong base (neutralization), which maked it soluble in 6% NaOH.
2. weak base, i.e. 6% Na2CO3 has a mild reaction with weak acid, which maked it appear like insoluble.
3. weak acid does not react with acid, i.e. 6% HCl, which made it appear insoluble.
4. weak organic acids (not sure if all) are not soluble (or slightly soluble) in water.
5. Organic compounds are usually more soluble in organic solvent (diethyl ether) than in water. That is the so called "alike" likes "alike".